Subjects

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BI1.1 — Describe the molecular and functional organization of a cell and its sub-cellular components.

BI2.1 — Explain fundamental concepts of enzyme, isoenzyme, alloenzyme, coenzyme & co-factors. Enumerate the main classes of IUBMB nomenclature.

BI2.2 — Observe the estimation of SGOT & SGPT

BI2.3 — Describe and explain the basic principles of enzyme activity

BI2.4 — Describe and discuss enzyme inhibitors as poisons and drugs and as therapeutic enzymes

BI2.5 — Describe and discuss the clinical utility of various serum enzymes as markers of pathological conditions.

BI2.6 — Discuss use of enzymes in laboratory investigations (Enzyme-based assays)

BI2.7 — Interpret laboratory results of enzyme activities & describe the clinical utility of various enzymes as markers of pathological conditions.

BI3.1 — Discuss and differentiate monosaccharides, di-saccharides and polysaccharides giving examples of main carbohydrates as energy fuel, structural element and storage in the human body

BI3.2 — Describe the processes involved in digestion and assimilation of carbohydrates and storage.

BI3.3 — Describe and discuss the digestion and assimilation of carbohydrates from food.

BI3.4 — Define and differentiate the pathways of carbohydrate metabolism, (glycolysis, gluconeogenesis, glycogen metabolism, HMP shunt).

BI3.5 — Describe and discuss the regulation, functions and integration of carbohydrate along with associated diseases/disorders.

BI3.6 — Describe and discuss the concept of TCA cycle as a amphibolic pathway and its regulation.

BI3.7 — Describe the common poisons that inhibit crucial enzymes of carbohydrate metabolism (eg; fluoride, arsenate)

BI3.8 — Discuss and interpret laboratory results of analytes associated with metabolism of carbohydrates.

BI3.9 — Discuss the mechanism and significance of blood glucose regulation in health and disease.

BI3.10 — Interpret the results of blood glucose levels and other laboratory investigations related to disorders of carbohydrate metabolism.

BI4.1 — Describe and discuss main classes of lipids (Essential/non-essential fatty acids, cholesterol and hormonal steroids, triglycerides, major phospholipids and sphingolipids) relevant to human system and their major functions.

BI4.2 — Describe the processes involved in digestion and absorption of dietary lipids and also the key features of their metabolism

BI4.3 — Explain the regulation of lipoprotein metabolism & associated disorders.

BI4.4 — Describe the structure and functions of lipoproteins, their functions, interrelations & relations with atherosclerosis

BI4.5 — Interpret laboratory results of analytes associated with metabolism of lipids

BI4.6 — Describe the therapeutic uses of prostaglandins and inhibitors of eicosanoid synthesis.

BI4.7 — Interpret laboratory results of analytes associated with metabolism of lipids.

BI5.1 — Describe and discuss structural organization of proteins.

BI5.2 — Describe and discuss functions of proteins and structure-function relationships in relevant areas eg, hemoglobin and selected hemoglobinopathies

BI5.3 — Describe the digestion and absorption of dietary proteins.

BI5.4 — Describe common disorders associated with protein metabolism.

BI5.5 — Interpret laboratory results of analytes associated with metabolism of proteins.

BI6.1 — Discuss the metabolic processes that take place in specific organs in the body in the fed and fasting states.

BI6.2 — Describe and discuss the metabolic processes in which nucleotides are involved.

BI6.3 — Describe the common disorders associated with nucleotide metabolism.

BI6.4 — Discuss the laboratory results of analytes associated with gout & Lesch Nyhan syndrome.

BI6.5 — Describe the biochemical role of vitamins in the body and explain the manifestations of their deficiency

BI6.6 — Describe the biochemical processes involved in generation of energy in cells.

BI6.7 — Describe the processes involved in maintenance of normal pH, water & electrolyte balance of body fluids and the derangements associated with these.

BI6.8 — Discuss and interpret results of Arterial Blood Gas (ABG) analysis in various disorders.

BI6.9 — Describe the functions of various minerals in the body, their metabolism and homeostasis.

BI6.10 — Enumerate and describe the disorders associated with mineral metabolism.

BI6.11 — Describe the functions of haem in the body and describe the processes involved in its metabolism and describe porphyrin metabolism.

BI6.12 — Describe the major types of haemoglobin and its derivatives found in the body and their physiological/ pathological relevance.

BI6.13 — Describe the functions of the kidney, liver, thyroid and adrenal glands.

BI6.14 — Describe the tests that are commonly done in clinical practice to assess the functions of these organs (kidney, liver, thyroid and adrenal glands).

BI6.15 — Describe the abnormalities of kidney, liver, thyroid and adrenal glands.

BI7.1 — Describe the structure and functions of DNA and RNA and outline the cell cycle.

BI7.2 — Describe the processes involved in replication & repair of DNA and the transcription & translation mechanisms.

BI7.3 — Describe gene mutations and basic mechanism of regulation of gene expression.

BI7.4 — Describe applications of molecular technologies like recombinant DNA technology, PCR in the diagnosis and treatment of diseases with genetic basis.

BI7.5 — Describe the role of xenobiotics in disease

BI7.6 — Describe the anti-oxidant defence systems in the body.

BI7.7 — Describe the role of oxidative stress in the pathogenesis of conditions such as cancer, complications of diabetes mellitus and atherosclerosis.

Biochemistry Syllabus, Notes & PYQ for GGSIPU Bachelor of Medicine and Bachelor of Surgery Phase 1